Han Lab
Jian Han, M.D., Ph.D. (read bio)
Faculty Investigator
contact
Research interests
- Developing integrated solutions for molecular differential diagnosis. Biochemical reactions, such as the polymerase chain reaction, are like software in the IT industry, they require tailor-made hardware to become more functional. Dr. Han is developing an integrated technology platform that allows multiplexmolecular differential diagnoses carried out in a fashion that is high throughput, semi-quantitative, automatic, and with a closed system.
- Applying the multiplex PCR technology, Dr. Han is developing a method to study interactions between our immune system and the environment.
Information for the scientific community on Dr.Han's latest project can be found by going to the personal webpage The Repertoire 10K (R10K) Project.
HudsonAlpha initiates study to examine disease risk
R10K will include 10,000 patient samples
HUNTSVILLE, Ala. -Dr. Jian Han, faculty investigator at the HudsonAlpha Institute for Biotechnology, has announced a major project that aims to help identify risks for 100 human diseases. The Repertoire 10K Project will sequence the immune repertoire of 10,000 individuals with specific disease histories and then seek to identify T and B cell receptor sequences associated with these specific diseases.
HudsonAlpha researcher Jian Han, M.D., Ph.D., teams up with UAH researcher to identify invasive plant species
News Outlet:
Newswise
Date published:
April 28, 2013 
HUNTSVILLE, Ala. — University of Alabama in Huntsville assistant biology professor Dr. Leland Cseke and HudsonAlpha Institute for Biotechnology researcher Dr. Jian Han have joined forces to identify invasive plant species that are sneaking into the United States because they look just like desirable crops or ornamentals.
Co-detection of Pandemic (H1N1) 2009 Virus and Other Respiratory Pathogens
News Outlet:
Emerging Infectious Disease
Date published:
December 1, 2010
Download PDF:
Members of the Han Lab at HudsonAlpha and employees at Diatherix Laboratories were recently published in a paper about the 2009 H1N1 oubreak.
Download the PDF above or access the paper here.
“Most Promising” China Life Science Companies Named at BioBay Investor Forum
News Outlet:
BusinessWire
Date published:
November 5, 2010
Download PDF:
BeiGene LLC and Suzhou KeyBay Biotechnology Inc. Selected by a Panel of VCs and Pharma Executives as Most Likely to Succeed
Tailoring treatment
News Outlet:
The Huntsville Times R&D Report
Date published:
September 5, 2010
Download PDF:
By Wendy Reeves
Award-winning HudsonAlpha researcher's iCubate device shortens pathogen identification time.
Read the full article by opening the attached PDF or by viewing The Huntsville Times R&D Report online.
Researchers turn to immune repertoire sequencing to better understand disease
News Outlet:
GenomeWeb
Date published:
August 31, 2010
Download PDF:
By Monica Heger
As next-generation sequencing gains more traction in labs, researchers are increasingly using the technology to understand more complex human systems such as the immune repertoire.
Dr. Jian Han and fellow scientists at the HudsonAlpha Institute for Biotechnology were recently published with the paper—High throughput sequencing reveals a complex pattern of dynamic interrelationships among human T cell subsets—in the journal Proceedings of the National Academy of Sciences. Swine flu test developed here gets 'emergency' OK
News Outlet:
The Huntsville Times
Date published:
October 15, 2009
Download PDF:
Technology checks many pathogens, speeds treatment
By Patricia McCarter
Times Staff Writer
Although it can take years for federal regulators to approve a new drug or medical test, the Food and Drug Administration has granted the Huntsville-produced Diatherix H1N1-09 influenza test "emergency use authorization."
Diatherix Laboratories to make test available to physicians
